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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image01 December 2025 Vol. No. 14 ; Issue No.711
Publications

1. Shetty MP, Sule P, Kulkarni SD, Chaudhari P, Bharati S (2025). Asialoglycoprotein receptor-mediated delivery of copper to hepatic tumors exerted inhibitory effect on tumor growth and progression. Biometals.

2. Nandy K, Parray A, Dhaiya A, Chopde A, Menon V, Ostwal V, Ramaswamy A, Bhargav P, Bhandare MS, Shrikhande SV, Chaudhari VA (2025). The Role of HIPEC in Isolated Cytology-Positive Gastric Cancer: Nodal Metastasis Dominates Prognosis, HIPEC Remains Unproven. Annals of Surgical Oncology.

3. Ghosh M, Hoysal DR, Deshpande A, Badwe RA (2025). Letter to the Editor "Impact of Time to Surgery Post Neoadjuvant Chemotherapy on Breast Cancer Outcomes: A Retrospective Study of Patients Enrolled in the I-SPY 2 Clinical Trial". Annals of Surgical Oncology.

4. Palkar PA, John G, Chekuri G, Chatterjee A, Kunwar A, Goda JS. Radioprotectors & mitigators in radiation therapy: Harnessing diverse pathways for optimizing clinical outcomes. Indian Journal of Medical Research. 162(3):343-366.

5. Masrani N, Tulsian A, Shetty SS, Patil V, Qureshi SS (2025). Uncommon Location for Pelvic Ganglioneuroblastoma: Pelvic Nebenorgane. Journal of Indian Associaiton of Pediatric Surgeons. 30(6):789-791.

6. Mhatre S, Dutta D, Iyer A, Golapkar SV, Mishra A, Krishnatreya M, George GS, Doibale PN, Dun Y, Wang Z, Jahagirdar O, Chaturvedi P, Rajaraman P, Wang CP, Chaturvedi A, Kar S, Dikshit R, Chatterjee N (2025). A genome-wide association study of buccal mucosa cancer in India and multi-ancestry meta-analysis discovers risk loci and gene-environment interactions. EBioMedicine.

7. Jain Y, Shukla V, Tripathi M, Venkatachalam M, Suresh A, Kapoor A, Pujari L, Chowdhury Z, Thakur S, Manda D, Kalra S, Purandare N (2025). Role of Gallium 68 fibroblast activation protein inhibitor PET/CT in the initial evaluation of gastric adenocarcinoma: a single-institution retrospective study. Nuclear Medicine Communications.

Site of the Week

The DICE (Database of Immune Cell Expression, Expression quantitative trait loci (eQTLs) and Epigenomics) aims to understand the role of common genetic variations in human disease.

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Interesting Reads

White M, Mills ML, Millett LM, Gilroy K, Hong Y, Zeiger LB, Simpson RJ, Corry SM, Ligeza A, Lannagan TRM, Susanti S, Ridgway RA, Yazgili AS, Grzesiak L, Amirkhah R, Ford CA, Vlahov N, Tovell H, Officer-Jones L, Ficken C, Pennie R, Najumudeen AK, Raven A, Nasreddin N, Chauhan E, Papanastasiou AS, Nixon C, Morrison V, Jackstadt R, Graham JS, Miller CJ, Ross SJ, Barry ST, Pavet V, Wilson RH, Le Quesne J, Dunne PD, Tejpar S, Leedham S, Campbell AD, Sansom OJ (2025). MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance. Nature.

Video of the Week
Tumor Extracellular Vesicles and Particles Promote Metastasis and Systemic Disease
Upcoming Events
21st National Research Scholars Meet - NRSM

December 16-17, 2025

At ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai

TMC Head & Neck Rehabilitation & Survivorship Conference 2025

December 20-21, 2025

At Seminar Room, 7th Floor, RRU, ACTREC,Kharghar

Workshop on Fundamentals of Cervical Cancer Screening, Colposcopy & Pre-cancer Management

January 15-16, 2026

At ACTREC, Tata Memorial Centre, Kharghar

Do You Know?

In 1918, Physicist Gioacchino Failla, who worked at Memorial Sloan Kettering, developed the first external-beam radium therapy device, known as a “radium element pack.” The device is used to treat cancers located in the chest, brain, and abdomen.

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Cancer News
New Genome-Wide Study from Tata Memorial Centre Reveals: “Why Do Some Tobacco Chewers Develop Oral Cancer Early?”

Press Information Bureau, 29/11/2025

This landmark study represents a significant advance in our understanding of the genetic and environmental factors driving buccal mucosa cancer, a disease that imposes a heavy burden in India and across South Asia. By conducting the largest genome-wide association study of its kind and integrating...

Tata Memorial finds way to kill drug-resistant cancer cells: What this breakthrough means for aggressive breast cancer

Indian Express, 27/11/2025

Researchers have found a critical vulnerability in triple-negative breast cancer, which makes up almost 31 per cent of breast cancer cases in India.Led by Dr Nandini Verma, principal investigator from the Cancer Research Institute (CRI) division of TMC-ACTREC, they have found that although chemotherapy kills...

Missing cancer gene may boost response to immunotherapy

News-Medical, 26/11/2025

The research team found that the missing tumor-driving gene, known as PRKCI, results in tumors that are less aggressive. The missing gene also cultivates a more powerful immune response to tumors. Surprisingly, the research team found the improved immune response occurs with help from unexpected...

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